When you first meet someone, you usually shake them ......... the hand

When you first meet someone, you usually shake them ......... the hand. (*) with (*) on (*) in (*) by


This is a companion discussion topic for the original entry at https://english.best/questions/870,when-you-first-meet-someone-you-usually-shake-them-___-the-hand/
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I don’t think shaking people by their hands is a good idea nowadays.

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You can shake somebody by the hand or you can shake somebody’s hand, especially when you meet them for the first time, however, I found the following sentence in the Cambridge dictionary online:

The Princess was photographed shaking hands with AIDS victims.

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