What are the difference between safe and secure?

For your safety and security, please don’t open this door.

What is the difference between these two words?

Thank you in advance for any explanation.

In this sentence, I fear there is no difference at all: it rather seems as though its author were someone who likes to stick on meaningless words in order to look more distinguished; security doesn’t appear to add anything that safety didn’t have yet.

In some contexts, however, there may be a difference. You could look up both words in an online dictionary; secure is mostly used for situations where something is locked away; safe for situation where something is protected from harm. But then we have a safe, which is a locked container; and on the other hand a security guard, who will often protect against robbers and such.

Thank you so much, Cerberus. It makes sense.