Spring brings with it signs of

Spring brings with it signs of renewal that make itself/themselves known in a thousand ways.
Spring brings with it sign of renewal that makes itself/themselves known in a thousand ways.

  1. Which one is correct at the bold part?
  2. Are the sentences correct?

‘Themselves’ is correct here because it relates to ‘signs’ and this is plural.

The second sentence using the singular form should be
Spring brings with it a sign of renewal that makes itself known in a thousand ways.

Spring brings with its a sign of renewal that makes itself known in a thousand ways.

Is there any problem now?

Yes. ‘its’ is incorrect. You need ‘it’ there. (Spring brings with itself)

Spring brings with it a sign of renewal…
just as I wrote above.