is of interest vs is interesting

  1. Family history is of interest across a wide range of ages and may even motivate people to use the Internet and computers.
  2. Family history is interesting across a wide range of ages and may even motivate people to use the Internet and computers.
    Can I replace “is of interest” by “is interesting” as in #2?
    If it is possible, is there any difference in meaning between them? which one do you prefer?

Not really. The original is the better of the two options.

Thanks a lot!
I would like to ask you one more question.
Is there any rule for your choice or it is something that I have to learn by heart?

Beeesneees,

  1. Astronomy in particular is of interest to people at all levels.
  2. Astronomy in particular is interesting to people at all levels.
    Do both sentences mean the same?
  1. Astronomy, in particular, is of interest to people at all levels.
  2. Astronomy, in particular, is interesting to people at all levels.

The first utilises a set expression and is the most fluent of the two.

to be of interest to is a set expression.