It is hard to believe

It is hard to believe, but last spring Emma, then 6, was near death from leukemia. She had relapsed twice after chemotherapy, and doctors had run out of options.
What does the bold part suggest?

That the doctors could not find/think of any treatment that might work.

Hi RC,

I think this expression ‘run out of’ needs a closer definition. It suggests that you have nothing more left - in the sentence you quote the doctors had used up all their options and had none left. On a mundane level you would say: As we have run out of coffee, we’ll have to go and buy some at the local store.


“We were afraid he might relapse into a coma for second time.”
Is this sentence OK?
Can we omit the article ‘a’ from the sentence?


You would have to say: a coma for the second time.