Are 'set off' and 'take off' interachangeable?

English as a Second Language English Vocabulary, Grammar and Idioms
1

Did I use these phrasal verbs correct?

  1. I took off for a long journey.

  2. I set off for a long journey.

  3. Today I took off to the office earlier than usual.

  4. Today I set off to the office earlier than usual.

I would also like to know if the sentence below is correct.
5) The teacher asked the children to finish their work for classwork. (Instead of saying in class, can I say for classwork?)

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2

They have the same meaning, but in AmE people almost never say “set off”.

From most to least common in AmE.

I left on a long trip.
I took off on a long trip.
I set off on a long trip.

“Class” works much better in that sentence. You could also say something like:

The teacher asked the children to finish and turn in their homework.
The teacher asked the children to finish and turn in their assignment.
The teacher asked the children to finish and turn in their classwork.

Homework is the most commonly used word.

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3

Thanks @NearlyNapping for your help.
Are sentences 3 and 4 correct as well?

  1. Today I took off to the office earlier than usual.
  2. Today I set off to the office earlier than usual.
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4

Both are OK. Although “left for the office” is more common.
‘Left for work’ is also common.

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5

@NearlyNapping Thanks for your help

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